Cardiac resynchronization therapy guided by activation mapping in non-left bundle branch block patients

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Various studies have questioned the magnitude benefit cardiac resynchronization therapy (CRT) in patients without left bundle branch block (LBBB). This worse response could be due to suboptimal location electrodes. Purpose We hypothesize that non-LBBB patients, an implant guided by ventricular electroanatomic mapping locating areas with greatest activation delay will improve outcome CRT. Material and methods included 7 non-LBBB. To locate most delayed zones, electromagnetic map was created using Ensite Precision navigator connected right catheter a guidewire electrical recording capacity at its distal end. ECG, clinical, echocardiographic data were recorded baseline post-implantation, compared LBBB (control group). Results In several patterns defined according conduction disorder, including (RBBB)+left anterior hemiblock (figure 1A) or RBBB alone 1B). All improved follow-up NYHA functional class (p=0,011) Minnesota test (7,85±4,63; p=0.004). The mean reduction QRS duration 14,57±9,86 ms (p=0.008), LVEF increased 8.22±4.62 (p=0.003), LVOTS decreased 15,71±12,23 ml (p=0.015) LVEDV 10,42±5,15 (p=0.002). There no significant differences between CTR (table 1), (8.22±4.62 vs 11.54±5.54, p=0.248) difference (7.85±4.63 9.71±5.87, p=0.524). Conclusions CRT electroanatomical produced clinical structural improvement patients. similar disorder observed.